Dr. Michael Bennett, MD
Board-Certified Gastroenterologist
The mechanism here isn't new or controversial. Osmotic agents have been the non-stimulant option for a long time, and magnesium oxide in particular has a long clinical history outside the United States.
What I'd want a patient to understand is the distinction between osmotic and stimulant approaches. Stimulant laxatives act on the bowel wall to force contraction. Osmotic agents don't act on nerve or muscle at all. That difference matters for anyone thinking about long-term use.
Chronic constipation should always be evaluated by a physician first to rule out anything structural.
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